姓  名: 鄒 振
學  科: 基因組學
電話/傳真: +86-10-64807191 / +86-10-64807099
電子郵件: zouzhen@ioz.ac.cn
通訊地址: 北京市朝陽區北辰西路1號院5號
必威精装版app西汉姆联 農業蟲害鼠害綜合治理研究國家重點實驗室 100101
更多信息: 昆蟲免疫和發育研究組     

簡曆介紹:

  鄒振,男,博士,研究員,博士生導師;必威精装版app西汉姆联 昆蟲免疫和發育研究組課題組組長。
1997年於華東理工大學獲得生物化學工程學士學位,2005年於美國俄克拉荷馬州立大學獲得昆蟲學博士學位。其後分別在俄克拉荷馬州立大學和加州大學河濱分校進行博士後研究,於2010.10起擔任助理研究員。2012年7月,任必威精装版app西汉姆联 昆蟲免疫和發育學研究組組長,研究員,博士生導師。現任中國昆蟲學會常務理事、中國昆蟲學會國際交流合作工作委員會主任、昆蟲發育與遺傳專業委員會、昆蟲生理生化與分子生物學專業委員會委員、中華預防醫學會媒介生物學及控製分會委員、北京市昆蟲學會常務理事、昆蟲學報編委、中國媒介生物學及控製雜誌編委。

  主要從事分子生物學和媒介生物學的研究,聚焦於昆蟲天然免疫和發育,首先以鱗翅目害蟲和吸血昆蟲這兩類昆蟲為研究對象,利用寄生蜂、真菌等外緣生物控製因子,整合生理、生化、細胞、分子、遺傳和組學研究方法和手段,在細胞、器官和個體水平上,對昆蟲免疫、生殖發育等方麵進行研究。發表SCI論文四十多篇,以主要作者發表於Immunity, PNAS, EMBO Report, Nature Commun, PLoS Genetics, PLoS Pathogens等SCI期刊上。為DCI, IBMB, BMC Genomics, PLoS One等20種雜誌審稿人。

研究領域:

  目前有三個相輔相成的研究重點:非脊椎動物免疫係統的比較進化:衛生和農業昆蟲的抗真菌、抗病毒免疫反應,激素調控的昆蟲生殖生物學。

社會任職:

獲獎及榮譽:

  2005年度國家優秀留學生獎學金、2005年度美國昆蟲學會的Student Recognition Award in Insect Physiology, Biochemistry, Toxicology, and Molecular Biology、2017。

承擔科研項目情況:

代表論著:

  1. Yuan C, Xing L, Wang M, Wang X, Yin M, Wang Q, Hu Z#, and Zou Z# (2017). Inhibition of melanization by serpin-5 and serpin-9 promotes baculovirus infection in cotton bollworm Helicoverpa armigera. PLoS Pathog13, e1006645.
  2. Wang X, Hou Y, Saha TT, Pei G, Raikhel AS#, Zou Z#. Hormone and receptor interplay in the regulation of mosquito lipid metabolism. Proc Natl Acad Sci U S A. 2017; 114(13):E2709-E2718. doi: 10.1073/pnas.1619326114.
  3. Wang Y, Jiang H, Cheng Y, An C, Chu Y, Raikhel AS, Zou Z#. Activation of Aedes aegypti prophenoloxidase-3 and its role in the immune response against entomopathogenic fungi. Insect Mol Biol. 2017 May 27. doi: 10.1111/imb.12318.
  4. Xing L, Yuan C, Wang M, Lin Z, Shen B, Hu Z, Zou Z#. Dynamics of the interaction between cotton bollworm Helicoverpa armigera and nucleopolyhedrovirus as revealed by integrated transcriptomic and proteomic analyses. Mol Cell Proteomics.2017; pii: mcp.M116.062547. doi: 10.1074/mcp.M116.062547.
  5. Zhao LL, Zhang X, Wei Y, Zhou J, Zhang W, Qin P, Chinta S, Kong X, Liu Y, Yu H, Hu S, Zou Z#, Butcher RA#, Sun JH#. Ascarosides coordinate the dispersal of a plant-parasitic nematode with the metamorphosis of its vector beetle. Nat Commun. 2016; 7:12341, doi: 10.1038/ncomms. 12341.
  6. Zhao B, Hou Y, Wang J, Kokoza VA, Saha TT, Wang XL, Lin L, Zou Z#, Raikhel AS#. Determination of juvenile hormone titers by means of LC-MS/MS/MS and a juvenile hormone-responsiveGal4/UAS system in Aedes aegypti mosquitoes. Insect Biochem Mol Biol. 2016; 77:69-77, doi: 10.1016/j.ibmb. 2016.08.003.
  7. Roy, S., Saha, T. T., Johnson, L., Zhao, B., Ha, J., White, K. P., Girke, T., Zou, Z#. and Raikhel, A. S#. Regulation of gene expression patterns in mosquito reproduction. PLoS Genet. 2015; 11(8), e1005450. doi: 10.1371/journal.pgen. 1005450. 
  8. Hou, Y., Wang X.L., Saha, T.T., Roy, S., Zhao, B., Raikhel, A.S.#, Zou Z#. Temporal Coordination of Carbohydrate Metabolism during Mosquito Reproduction. PLoS Genet. 2015; 11(7): e1005309. doi: 10.1371/journal.pgen. 1005309.
  9. Meng, Q., Yu, H.Y.,  Zhang, H., Zhu, W., Wang, M.L., Zhang, J.H., Zhou, G.L., Li, X., Qin, Q.L.#, Hu, S.N.#, Zou, Z#.  Transcriptomic insight into the immune defenses in the ghost moth, Hepialus xiaojinensis, during an Ophiocordyceps sinensis fungal infection. Insect Biochem Mol Biol. 2015; 64:1-15. doi: 10.1016/j.ibmb. 2015.06.014.
  10. Wang, Y.H., Hu, Y., Xing, L.S., Jiang, H., Hu, S.N., Raikhel, A.S. #, Zou, Z#. A Critical Role for CLSP2 in the Modulation of Antifungal Immune Response in Mosquitoes. PLoS Pathog. 2015; 11(6):e1004931. doi: 10.1371/journal.ppat. 1004931.
  11. Xiong, G.H., Xing, L.S., Lin, Z., Saha, T.T., Wang, C., Jiang, H., Zou, Z#. High throughput profiling of the cotton bollworm Helicoverpa armigera immunotranscriptome during the fungal and bacterial infections. BMC Genomics. 2015; 16(1):321. doi: 10.1186/s12864-015-1509-1.
  12. Zou, Z.*, Saha, T.T.*, Roy, S.*, Shin, S.W., Backman, T.W., Girke, T., White, K.P., and Raikhel, A.S. Juvenile hormone and its receptor, methoprene-tolerant, control the dynamics of mosquito gene expression. Proc Natl Acad Sci U S A. 2013; 110(24): E2173-81. doi: 10.1073/pnas.1305293110.
  13. Zou, Z.*, Souza-Neto, J.A.*, Xi, Z., Shin, S.W., Alvarez, K.S., Kokoza, K., Dimopoulos, G., Raikhel, A.S. Transcriptome Analysis of Aedes aegypti Transgenic Mosquitoes with Altered Immunity. PLoS Pathog. 2011; 7(11):e1002394. doi: 10.1371/journal.ppat.1002394.
  14. Zou, Z.*, Shin, S.W.*, Alvarez, K.S., Kokoza, K., Raikhel, A.S. Distinct melanization pathways in the mosquito Aedes aegypti. Immunity. 2010; 32(1):41-53. doi: 10.1016/j.immuni.2009.11.011.
  15. Zou, Z.*, Shin, S.W.*, Alvarez, K.S., Bian, G., Kokoza, K., Raikhel, A.S. Mosquito RUNX4 in the immune regulation of PPO gene expression and its effect on avian malaria parasite infection. Proc Natl Acad Sci U S A. 2008; 105(47):18454-9. doi: 10.1073/pnas.0804658105.
  16. Zou, Z., Evans, J., Lu, Z., Zhao, P., Williams, M., Sumathipala, N., Hetru, C., Hultmark D., Jiang H. (2007) Comparative genomic analysis of the Tribolium immune system. Genome Biol.2007; 8(8):R177. doi:  10.1186/gb-2007-8-8-r177.
  17. Zou, Z., Jiang, H. Manduca sexta serpin-6 regulates immune serine proteinases PAP-3 and HP8. cDNA cloning, protein expression, inhibition kinetics, and function elucidation. J Biol Chem. 2005; 280(14), 14341-8. doi: 10.1074/jbc.M500570200.

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